Gelatin don Hard Capsules
Tare da ci gaban masana'antun magunguna, hadaddun da tsauraran buƙatun ayyuka da yawa ana sanya su gaba don aiwatar da kayan, waɗanda ke da wahalar haɗuwa da yawancin kayan ƙarfe da kayan inorganic.
Gelatin wani abu ne na polymer na halitta, wanda yana da tsari mai kama da kwayoyin halitta.Yana da kyawawan kaddarorin jiki da sinadarai, biocompatibility, biodegradability, kazalika da sauƙin samarwa, sarrafawa da halayen gyare-gyare, yana sa ya zama cikakkiyar fa'ida a fagen biomedicine.
Lokacin amfani da gelatin Pharmaceutical don samar da m wuya capsules, yana da manyan halaye irin su dace danko a babban taro, high inji ƙarfi, thermal invertibility, wani low / dace daskarewa batu, isasshen ƙarfi, high nuna gaskiya da sheki na gelatin cewa forms. bangon capsule.
Dalilin da ya sa gelatin magani yana da dogon tarihi shine cewa an haifi capsule mai laushi na farko na gelatin a cikin 1833. Tun daga wannan lokacin, gelatin ya kasance ana amfani da shi sosai a masana'antar harhada magunguna kuma ya zama wani ɓangare na ba makawa.
| Matsayin Gwaji: China Pharmacopoeia Shekarar 2015 2 | Don Hard Capsule |
| Abubuwan Jiki da Sinadarai | |
| 1. Ƙarfin Jelly (6.67%) | 200-260 furanni |
| 2. Dankowa (6.67% 60 ℃) | 40-50mps |
| 3 Tsaki | 4-60 guda |
| 4. Danshi | ≤12% |
| 5. Toka(650℃) | ≤2.0% |
| 6. Bayyanar (5%, 40 ° C) mm | ≥500mm |
| 7. PH (1%) 35 ℃ | 5.0-6.5 |
| ≤0.5mS/cm |
| Korau |
| 10. Watsawa 450nm | ≥70% |
| 11. Watsawa 620nm | ≥90% |
| 12. Arsenic | ≤0.0001% |
| 13. Chrome | ≤2pm |
| 14. Karfe masu nauyi | ≤30ppm |
| 15. SO2 | ≤30ppm |
| 16. Abu maras narkewa a cikin ruwa | ≤0.1% |
| 17 .Jimlar adadin ƙwayoyin cuta | ≤10 cfu/g |
| 18. Escherichia coli | Mara kyau/25g |
| Salmonella | Mara kyau/25g |
